Paternity Testing Research Today is a free monthly online journal that collates and summarizes the latest research about Paternity Testing, including details on accuracy, methods, procedure, dna testing.

Influence of duration of sexual cohabitation on the risk of hypertension in nulliparous parturients in Ibadan: A cohort study.

Olayemi O, Strobino D, Aimakhu C, Adedapo K, Kehinde A, Odukogbe AT, Salako B

Department of Obstetrics and Gynaecology, College of Medicine, University of Ibadan, Ibadan, Nigeria.

Background: Hypertensive disorders of pregnancy are an important cause of maternal mortality in this environment, it accounts for about 20% of all maternal deaths in pregnancy in Nigeria. Aim: This study aims to determine the effect of the length of sexual cohabitation on the development of hypertension in pregnancy in a Nigerian population. Materials and methods: The study was a prospective cohort study; three centres were involved in the study between July 2006 and February 2009. For this study, the main outcome variable was the development of Hypertension in pregnancy. The main explanatory variable was the length of preconception sexual cohabitation. Univariate analysis was by t test, chi-squared test and Fisher's exact test for continuous and categorical variables. Multivariate analysis was by Cox hazard regression Results: In the study population, the incidence of gestational hypertension and pre-eclampsia were 28.93% and 4.13% respectively, 29.64% had previous abortions and same paternity abortion rate was 25.92%. Length of sexual cohabitation before index pregnancy was protective against hypertension in pregnancy but not for pre-eclampsia; there was a 4% decrease in the risk of developing hypertension for every month increase in cohabitation (hazard ratio, HR 0.96 (95% CI 0.93-0.99)). Also protective in this model was same paternity abortion with a HR of 0.71 (95% CI 0.55-0.93). A previous abortion was not protective (HR 1.05 (95% CI 0.82-1.35)). Conclusion: It was concluded that increased length of sexual cohabitation prior to conception reduces the risk of gestational hypertension.

Published 11 March 2010 in Aust N Z J Obstet Gynaecol, 50(1): 40-4.
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Articles on Paternity Testing published 24 February 2010:

SNPs for a universal individual identification panel.   Hum Genet, 127(3): 315-24.

An efficient method to uniquely identify every individual would have value in quality control and sample tracking of large collections of cell lines or DNA as is now often the case with whole genome association studies. Such a method would also be useful in forensics. SNPs represent the best markers for such purposes. We have developed a globally applicable resource of 92 SNPs for individual identification (IISNPs) with extremely low probabilities of any two unrelated individuals from anywhere ... [Abstract] [Full-text]

A silent allele in the locus D19S433 contained within the AmpFlSTR Identifiler PCR Amplification Kit.   Leg Med (Tokyo), 12(2): 94-6.

We present two cases where a single locus mismatch was found in the locus D19S433 using the AmpFlSTR Identifiler PCR Amplification Kit (Applied Biosystems) (Identifiler Kit) during paternity and maternity tests. This mismatch differed from the mismatch pattern where there is usually a one repeat difference. We designed forward and reverse primers so that they were positioned further away from the primer set contained in the Identifiler Kit. The results showed the existence of a silent allele 13 ... [Abstract] [Full-text]

Articles on Paternity Testing published 5 February 2010:

Infanticide and reproductive restraint in a polygynous social mammal.   Proc Natl Acad Sci U S A, 107(5): 2130-5.

Alpha male chacma baboons experience uncontested access to individual estrus females. Consequently, alpha male paternity certainty is high and underpins significant levels of infanticide by immigrant males that, in turn, has selected for male defense of infants. There is also, however, a high probability that alpha males will be absent during the period when their own offspring are vulnerable, suggesting selection for additional countermeasures. We use data from a long-term study to test the ... [Abstract] [Full-text]

Articles on Paternity Testing published 3 February 2010:

Assessment of phylogenetic structure of Berber-speaking population of Azrou using 15 STRs of Identifiler kit.   Leg Med (Tokyo), 12(1): 52-56.

Allele frequencies for 15 STR autosomal loci of Identifiler kit (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA) in the Moroccan population of Berber-speaking of Azrou, were assessed from a sample of 201 unrelated individuals. Markers D18S51, D2S1338, FGA and D21S11 present the highest power of discrimination (PD) values while D21S11 was the most polymorphic locus in the studied population. The phylogenetic tree established ... [Abstract] [Full-text]

A novel application of 1H magnetic resonance spectroscopy: non-invasive identification of spermatogenesis in men with non-obstructive azoospermia.   Hum Reprod.

BACKGROUND About 10% of infertile men have no sperm in their ejaculate due to poor or absent spermatogenesis, also known as non-obstructive azoospermia (NOA). Testis (1)H magnetic resonance spectroscopy ((1)H-MRS) is a non-invasive imaging tool that can potentially identify and localize spermatogenesis in the testis. This study sought to identify metabolic signatures associated with various histological states of spermatogenesis in infertile men. METHODS Quantitative high resolution magic angle ... [Abstract] [Full-text]

Articles on Paternity Testing published 25 January 2010:

Ethical challenges in providing noninvasive prenatal diagnosis.   Curr Opin Obstet Gynecol.

PURPOSE OF REVIEW: Noninvasive prenatal diagnosis (NIPD) can potentially allow early detection of fetal genetic disorders, sex, other nonmedical traits, and paternity. We review ethical concerns associated with the imminent introduction of this testing. RECENT FINDINGS: There has been inadequate scientific and medical review of some NIPD tests under development or already available as direct-to-consumer products. Test introduction is largely unregulated and this has prompted calls for greater ... [Abstract] [Full-text]

Articles on Paternity Testing published 19 January 2010:

Ribonucleotide and ribonucleoside determination by ambient pressure ion mobility spectrometry.   Anal Chim Acta, 658(1): 91-7.

Detection limits and reduced mobilities for 12 ribonucleotides and 4 ribonucleosides were measured by ambient pressure electrospray ionization-ion mobility spectrometry (ESI-IMS). With the instrument used in this study it was possible to separate some of these compounds within mixtures. Detection limits reported for ribonucleotides and ribonucleosides ranged from 15 to 300 pmol and the reduced mobilities ranged from 41 to 56 suggesting that ambient pressure ESI-IMS may be used for their rapid ... [Abstract] [Full-text]

Articles on Paternity Testing published 13 January 2010:

Polyandry enhances offspring survival in an infanticidal species.   Biol Lett, 6(1): 24-6.

The adaptive significance of polyandry is an intensely debated subject in sexual selection. For species with male infanticidal behaviour, it has been hypothesized that polyandry evolved as female counterstrategy to offspring loss: by mating with multiple males, females may conceal paternity and so prevent males from killing putative offspring. Here we present, to our knowledge, the first empirical test of this hypothesis in a combined laboratory and field study, and show that multiple mating ... [Abstract] [Full-text]

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